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White Sox vs. Astros: Breaking down the 2026 season series

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Sometimes, the wild-card round of the Major League Baseball postseason gives fans thrilling and exciting matchups.

Other times, though, the wild-card round features a matchup of the two teams with the fewest combined wins (165) in a series in postseason history. That will be the case this week as the Chicago White Sox travel to Texas to take on the Houston Astros.

Let's dive into the season series between the two teams and see who has the advantage in the wild-card series.

What did the season series between Chicago and Houston tell us about the Astros?

The two teams met up seven times in the regular season, with Houston winning five of the seven games. Outside of a 12-run outburst from the White Sox in one of the seven games, Astros pitching held Chicago to five or fewer runs in the other six games.

Offensively for Houston, it was shortstop Jeremy Pena who carried the offense against Chicago. In 29 at-bats, Pena slashed .345/.367/.522 with two home runs, two RBI and a .918 OPS. 

On the pitching side, Astros ace Hunter Brown was stellar against the White Sox. He made two starts against them, going 2-0 with a 1.38 ERA and 14 strikeouts across 13 innings pitched.

Jeremy Peña leadoff home run as the Astros are going for a season-best six straight wins! pic.twitter.com/rHfbIoSaG1

— Talkin' Baseball (@TalkinBaseball_) July 26, 2026

Hunter Brown 7 STRIKEOUTS today vs White Sox@astros I #ChaseTheFight#Astros vs White Sox on SCHN & SCHN+ pic.twitter.com/ODQBmT4wmr

— Space City Home Network (@SpaceCityHN) September 3, 2026

What did the season series between Chicago and Houston tell us about the White Sox?

As noted above, it was a struggle offensively for the White Sox against the Astros in the regular season. There were, though, still some encouraging performances from some players.

Infielder Chase Meidroth did hit .304 in 23 at-bats with a home run and had four RBI. Additionally, first baseman Munetaka Murakami did have a two-home-run, six-RBI game in July but was rather quiet outside of that.

From a pitching perspective, right-hander Sean Burke was very good against Houston. He made two starts, going 1-1 with a 1.54 ERA and 16 strikeouts across 11 2/3 innings.

Munetaka Murakami bobblehead day blast! pic.twitter.com/4ZyEmT2oH7

— Chicago White Sox (@whitesox) July 26, 2026

Former Terp Sean Burke struck out six over 5.2 scoreless innings against the Astros last night, picking up his eighth win of the season pic.twitter.com/1DDqJniNw2

— Inside Maryland Sports (@Terrapins247) September 2, 2026

Who has the edge in the series?

Chicago's offense, especially in the slugging department, has been among the best in baseball this season. Its downfall, though, is its pitching, which ranks 15th in MLB in team ERA at 4.12.

Houston's pitching is even worse, ranking 24th in team ERA at 4.45. It truly feels like two or three high-scoring games will be the way this series plays out.

If that is the case, it's easy to side with the White Sox, but we haven't even mentioned Jose Altuve or Yordan Alvarez. Altuve is one of the most clutch hitters in postseason history, and Alvarez is the front-runner for American League MVP.

Those two experienced and veteran postseason bats will likely give Houston the edge in what has the potential to be the most underrated series in the first round.

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